Epidermal Growth Factor Receptor
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-286
CYS-287
2.4
2.3
27.1
-8.7
119.2
118.4
-62.6
CYS-287
GLY-288
5.5
5.7
64.1
-11.6
52.9
51.5
263.8
GLY-288
ALA-289
8.7
9.2
-19.7
-111.7
86.0
123.3
-344.5
ALA-289
ASP-290
12.2
11.6
120.8
-6.4
103.6
61.4
192.8
ALA-289
ASP-290
12.2
11.6
120.8
-6.4
103.6
61.4
192.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
ALA-289
ASP-290
12.2
11.6
120.8
-6.4
103.6
61.4
192.8
ALA-289
ASP-290
12.2
11.6
120.8
-6.4
103.6
61.4
192.8
ASP-290
SER-291
13.3
13.9
-2.5
-47.8
149.2
145.4
-288.7
SER-291
TYR-292
11.1
11.5
53.8
-106.4
96.4
107.9
-45.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
GLU-293
MET-294
7.4
7.5
81.6
-33.3
125.8
131.5
-195.8
MET-294
GLU-295
9.2
8.8
27.7
-20.1
133.2
113.3
-19.7
GLU-295
GLU-296
7.3
9.1
-14.6
-31.7
32.6
7.9
299.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LYS-311
VAL-312
13.5
13.7
-42.6
48.0
104.8
76.5
-24.6
VAL-312
CYS-313
9.8
9.9
54.3
-44.0
151.6
152.7
-82.2
CYS-313
ASN-314
8.0
8.2
30.7
-16.8
85.7
94.4
46.3
ASN-314
GLY-315
4.8
5.0
-164.8
173.1
75.2
46.7
-23.2
GLY-315
ILE-316
3.0
2.7
54.6
-42.1
125.9
135.4
-45.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees