Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  CYS-309   ARG-310  4.2 4.4 -7.7 -22.7 95.9 125.7 -9.6  ARG-310   LYS-311  1.0 1.0 20.4 74.4 32.5 35.8 78.2  LYS-311   VAL-312  1.5 1.8 -11.2 -5.5 93.9 86.3 4.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees