Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-77   MET-78  4.3 3.9 -6.3 7.3 37.3 40.0 23.1
 MET-78   LYS-79  1.8 1.3 -3.0 4.4 26.8 29.3 -28.1
 LYS-79   HIS-80  3.5 3.3 -14.6 9.1 58.0 51.3 58.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-82   VAL-83  4.3 4.4 25.3 -34.3 150.8 155.2 52.2
 VAL-83   ILE-84  3.5 3.7 -12.7 13.5 101.0 93.0 8.6
 ILE-84   GLY-85  4.9 5.1 -16.3 16.6 62.4 61.9 -45.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-106   HIS-107  10.5 10.5 4.2 -1.6 164.0 156.1 -81.9
 HIS-107   LEU-108  9.8 10.2 -3.1 38.3 90.3 95.2 -159.9
 LEU-108   MET-109  12.4 13.1 31.4 -66.1 140.6 108.0 152.1
 MET-109   GLY-110  10.5 12.7 154.9 119.0 134.2 96.9 350.8
 GLY-110   ALA-111  13.9 15.8 51.3 -18.0 70.8 91.0 61.1
 ALA-111   ASP-112  15.5 15.8 -28.0 -11.1 139.6 125.6 -252.6
 ASP-112   LEU-113  15.7 15.6 -2.2 19.4 60.9 56.0 -89.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-317   PRO-318  11.3 11.3 -2.4 -0.4 26.4 26.0 55.2
 PRO-318   VAL-319  10.2 10.2 2.5 -5.2 152.9 153.4 -11.8
 VAL-319   ALA-320  10.0 10.1 2.5 -15.3 114.9 116.8 55.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees