Nadp Isocitrate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASN-140   SER-141  1.5 1.2 0.0 -1.7 11.5 10.2 0.4  SER-141   ASP-142  1.8 1.8 -9.4 11.3 55.0 51.9 -9.0  ASP-142   ARG-143  3.5 3.0 -7.8 5.2 26.1 33.0 8.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-560   MET-561  3.6 4.1 -7.4 -42.7 56.2 56.0 136.7  MET-561   LEU-562  1.4 1.7 20.0 1.3 117.8 146.2 -94.3  LEU-562   SER-563  2.2 2.1 13.6 -9.3 156.5 142.9 -14.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees