Proto-Oncogene Cbl

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TRP-258   ASN-259  3.4 3.3 -19.3 9.5 27.2 32.8 55.5
 ASN-259   SER-260  3.8 3.7 -1.9 -13.6 71.2 71.9 -2.5
 SER-260   LEU-261  0.5 0.6 29.0 -15.2 60.8 51.7 -12.5
 LEU-261   ALA-262  2.0 1.9 -9.2 -1.6 99.7 101.1 -10.8
 ALA-262   VAL-263  4.3 3.9 59.0 -41.6 140.4 129.3 -5.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-268   MET-269  8.2 8.3 -11.3 21.9 77.1 74.2 -90.6
 MET-269   ALA-270  11.1 11.1 -110.5 103.9 38.0 50.3 -39.8
 ALA-270   PHE-271  11.1 9.8 -58.8 32.4 31.5 36.5 234.6
 PHE-271   LEU-272  13.4 11.6 54.1 -39.2 95.6 84.8 -5.9
 LEU-272   THR-273  14.6 14.2 15.5 7.4 146.5 144.9 -120.1
 THR-273   TYR-274  15.7 16.0 -13.8 0.7 105.3 110.4 -0.8
 TYR-274   ASP-275  16.7 17.0 8.9 0.9 67.2 67.9 2.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-293   ARG-294  10.2 10.2 -24.7 28.2 71.2 70.5 -65.3
 ARG-294   LEU-295  9.0 9.7 -25.2 -5.6 33.8 39.6 143.8
 LEU-295   SER-296  7.4 8.0 14.9 -59.7 129.5 132.8 160.3
 SER-296   CYS-297  9.0 9.6 -8.4 16.0 50.3 48.5 -14.0
 CYS-297   THR-298  10.3 10.4 15.9 -3.7 159.5 162.2 -108.3
 THR-298   ARG-299  9.9 10.0 1.9 0.0 96.6 92.0 26.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-300   GLY-301  4.8 4.6 11.4 -19.5 100.7 100.4 75.0
 GLY-301   GLN-302  1.7 1.5 17.6 -10.9 121.0 108.5 5.7
 GLN-302   TRP-303  4.9 4.6 4.3 -13.1 134.7 140.7 85.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees