Dual Specificity Mitogen-Activated Protein Kinase Kinase 6
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-81
LYS-82
2.7
4.6
-0.2
-30.9
70.9
57.3
19.5
LYS-82
ARG-83
2.7
5.4
15.5
21.9
118.8
110.4
-50.7
ARG-83
ILE-84
3.7
5.3
14.6
81.8
87.9
68.5
8.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-106
VAL-107
4.7
5.6
-8.4
1.2
96.1
76.2
-16.4
VAL-107
ASP-108
1.6
3.1
-12.1
2.3
109.3
95.0
-8.6
ASP-108
CYS-109
4.8
0.6
42.9
-74.1
104.9
127.3
12.1
CYS-109
PRO-110
5.5
3.8
24.2
-4.4
58.8
64.4
15.1
PRO-110
PHE-111
9.3
7.5
7.5
8.9
53.1
73.2
8.5
PHE-111
THR-112
9.9
8.9
-3.3
-5.3
132.7
141.7
-3.8
THR-112
VAL-113
7.1
7.0
4.8
-13.5
52.8
46.6
-5.4
VAL-113
THR-114
6.5
6.3
11.0
-22.6
98.7
84.2
-13.3
THR-114
PHE-115
5.2
3.3
-11.0
-3.5
137.5
161.3
-19.0
PHE-115
TYR-116
3.0
1.0
-1.0
8.9
102.3
95.5
3.7
TYR-116
GLY-117
5.9
2.9
16.3
-19.3
71.2
56.1
5.5
GLY-117
ALA-118
5.9
3.5
19.8
24.4
47.1
25.7
64.0
ALA-118
LEU-119
5.9
3.9
0.0
24.5
126.1
134.0
37.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees