Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  8.6 7.9 4.5 -2.3 141.8 139.6 -5.4
 ALA-640   ASP-641  6.2 5.4 -7.3 130.9 104.9 110.2 52.4
 ASP-641   PHE-642  3.2 3.1 68.1 149.9 78.8 146.0 -97.3
 PHE-642   GLY-643  1.3 5.3 23.2 -166.4 101.2 61.7 8.8
 GLY-643   LEU-644  2.9 4.4 177.2 -59.8 51.3 115.5 102.1
 LEU-644   ALA-645  4.5 4.3 -65.9 -7.8 96.7 100.8 64.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-663   VAL-664  6.4 7.4 -85.0 -14.1 21.8 54.0 108.0
 VAL-664   LYS-665  6.9 7.3 16.6 -7.2 130.5 130.3 -0.7
 LYS-665   TRP-666  5.4 5.4 4.5 8.7 80.3 72.7 -1.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees