Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PRO-193   ASP-194  0.6 0.9 6.2 3.2 79.8 74.4 2.9
 ASP-194   PHE-195  3.2 3.0 -18.3 -8.2 67.9 69.6 0.6
 PHE-195   TYR-196  4.5 4.4 22.7 7.3 37.3 45.7 64.5
 TYR-196   GLN-197  5.6 5.3 24.3 -15.3 64.4 56.3 19.4
 GLN-197   ALA-198  6.0 6.7 -4.0 4.0 65.0 63.6 6.5
 ALA-198   LYS-199  8.7 9.2 -4.4 -0.5 108.0 103.6 11.0
 LYS-199   ALA-200  10.3 10.2 -0.3 -7.9 155.1 157.9 -31.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-325   ALA-326  3.2 3.0 -17.1 -8.9 14.7 18.3 86.9
 ALA-326   SER-327  1.2 1.0 7.4 2.4 109.1 95.7 -15.4
 SER-327   HIS-328  3.1 3.3 -19.1 16.2 12.6 8.4 6.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 MET-463   GLY-464  5.6 6.9 -2.9 8.3 91.0 100.8 13.0
 GLY-464   ARG-465  3.8 4.6 18.3 -1.4 33.9 24.8 46.8
 ARG-465   TYR-466  3.4 3.9 -17.9 7.2 98.4 100.3 2.4
 TYR-466   ASN-467  4.1 4.1 -20.6 35.9 148.0 146.8 37.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees