Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
6.1
6.1
-7.7
5.2
48.4
50.6
4.6
LYS-114
GLY-115
5.7
5.9
-1.6
-6.4
70.3
66.0
18.8
GLY-115
PRO-116
2.3
2.4
9.9
-7.4
95.6
103.7
13.9
PRO-116
GLU-117
4.4
4.5
-53.2
25.5
26.9
32.4
108.1
GLU-117
ILE-118
6.9
6.4
-26.1
23.0
89.7
95.1
-31.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-215
ASP-216
10.5
10.1
-17.2
19.1
23.3
28.4
14.8
ASP-216
LEU-217
11.5
11.4
1.1
-22.4
134.8
138.8
70.8
LEU-217
PRO-218
8.8
8.6
-5.0
-6.7
53.2
71.1
12.0
PRO-218
ALA-219
7.2
6.7
3.1
-15.9
70.5
73.7
-8.2
ALA-219
VAL-220
5.1
3.9
16.2
-6.6
108.1
135.7
-27.6
VAL-220
SER-221
2.2
2.4
-37.6
0.7
67.3
51.1
85.6
SER-221
GLU-222
3.8
4.0
12.0
-9.9
158.4
152.0
-20.5
GLU-222
LYS-223
5.2
4.4
-1.6
3.4
87.0
92.8
2.0
LYS-223
ASP-224
5.9
5.4
4.7
-8.8
87.2
74.4
-3.4
ASP-224
ILE-225
3.1
2.7
5.4
-11.4
151.6
142.5
25.8
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees