Carboxyl-Terminal Src Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-235   GLU-236  10.0 10.4 -1.8 -1.4 61.1 60.0 10.6
 GLU-236   ALA-237  7.2 7.6 2.4 -0.9 66.7 64.8 -5.6
 ALA-237   SER-238  4.6 5.0 0.3 3.6 94.7 92.3 -15.0
 SER-238   VAL-239  6.5 6.7 0.0 -0.7 155.5 154.1 2.0
 VAL-239   MET-240  6.5 6.6 -6.3 2.9 80.8 79.9 8.2
 MET-240   THR-241  2.9 2.8 6.8 -7.4 64.6 63.6 -3.6
 MET-240   THR-241  2.9 2.8 6.8 -7.4 64.6 63.6 -3.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-240   THR-241  2.9 2.8 6.8 -7.4 64.6 63.6 -3.6
 MET-240   THR-241  2.9 2.8 6.8 -7.4 64.6 63.6 -3.6
 THR-241   GLN-242  4.8 4.5 11.3 -14.9 125.6 122.5 31.3
 GLN-242   LEU-243  7.2 7.0 12.0 -20.3 150.9 153.5 47.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-247   LEU-248  5.4 4.9 12.9 -17.8 118.5 119.2 20.1
 LEU-248   VAL-249  2.9 2.7 -5.1 2.8 39.2 37.5 5.2
 VAL-249   GLN-250  4.6 4.7 -10.9 10.3 38.7 40.5 20.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-265   THR-266  6.6 6.8 -3.6 1.1 38.5 37.3 23.6
 THR-266   GLU-267  6.4 6.9 10.9 -7.5 105.6 104.2 6.7
 GLU-267   TYR-268  8.9 9.6 12.1 -0.8 114.5 110.8 0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees