Metabotropic Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-186   PRO-187  2.1 2.5 -9.3 14.3 45.1 54.8 -7.7
 PRO-187   ASP-188  1.0 0.4 -11.3 26.7 112.0 119.9 18.0
 ASP-188   PHE-189  4.2 3.8 -34.4 -24.2 82.8 93.0 1.7
 PHE-189   PHE-190  6.7 5.8 43.7 -7.4 18.7 60.4 54.1
 PHE-190   GLN-191  6.6 5.6 16.1 -0.1 57.8 35.7 24.1
 GLN-191   ALA-192  6.6 6.8 27.5 7.8 105.0 97.0 -5.7
 ALA-192   LYS-193  9.8 10.2 8.4 -5.4 70.4 69.6 3.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-318   LEU-319  6.0 5.6 -5.9 -3.6 93.6 96.5 -3.2
 LEU-319   ALA-320  2.7 2.1 -4.1 -41.5 27.3 33.9 94.1
 ALA-320   SER-321  0.9 1.2 27.8 10.6 96.7 77.4 -1.5
 SER-321   TYR-322  4.4 4.8 -30.4 26.8 15.1 14.7 8.9
 TYR-322   PRO-323  6.5 6.6 11.8 -22.1 86.7 89.5 -23.1
 PRO-323   ILE-324  9.9 9.8 32.6 -41.2 97.2 94.4 -24.7
 ILE-324   SER-325  12.5 13.2 -42.8 9.5 43.3 53.5 37.5
 SER-325   ASP-326  15.0 15.4 159.2 -124.4 67.6 71.1 31.0
 ASP-326   PHE-327  18.6 18.6 -9.1 4.2 126.7 129.5 -19.2
 PHE-327   ALA-328  18.2 18.1 -4.3 2.8 61.6 61.4 -3.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-447   ASP-448  9.3 9.3 9.7 3.9 48.8 49.7 12.7
 ASP-448   GLY-449  6.4 6.5 -23.7 11.8 162.7 158.8 -3.2
 GLY-449   ILE-450  6.1 6.9 -42.5 12.8 105.2 122.8 -32.2
 ILE-450   GLY-451  6.0 7.6 -8.4 -46.4 108.9 142.9 -82.3
 GLY-451   ARG-452  4.5 4.9 106.0 -16.9 16.3 33.6 177.3
 ARG-452   TYR-453  3.7 4.3 5.7 5.9 77.4 77.3 20.6
 TYR-453   ASN-454  3.3 3.6 1.2 3.2 20.7 22.0 18.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees