Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  12.4 11.9 2.7 -2.1 76.0 73.6 -4.0
 ILE-639   ALA-640  8.9 8.3 11.5 -4.5 146.3 148.4 -7.9
 ALA-640   ASP-641  6.5 6.0 -19.1 -4.2 102.0 101.7 -9.1
 ASP-641   PHE-642  3.3 2.5 -20.3 -9.8 107.4 124.7 -14.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  11.9 13.0 17.2 52.6 116.7 95.1 -16.0
 LEU-662   PRO-663  9.2 12.4 -33.4 15.0 56.1 83.1 22.4
 PRO-663   VAL-664  7.3 8.8 -77.0 -25.2 13.5 37.6 108.0
 VAL-664   LYS-665  8.2 9.1 17.1 -11.1 132.5 137.9 3.2
 LYS-665   TRP-666  7.5 8.2 8.9 0.6 88.2 79.8 -3.1
 TRP-666   MET-667  4.0 4.9 0.1 4.2 96.9 94.0 1.3
 MET-667   ALA-668  3.9 4.3 1.3 5.8 157.8 155.8 -6.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees