Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-538   GLY-539  0.6 0.2 -3.7 14.5 82.9 83.0 12.6
 GLY-539   LYS-540  3.2 3.6 14.2 -24.4 153.0 161.8 51.6
 LYS-540   HIS-541  5.5 5.7 1.9 -1.2 98.1 100.0 29.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-544   ILE-545  3.3 3.5 25.3 -13.9 67.0 68.7 -9.6
 ILE-545   ASN-546  1.5 1.4 -17.8 -1.6 42.3 34.9 103.0
 ASN-546   LEU-547  4.4 4.1 9.3 1.5 85.1 85.9 49.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-562   TYR-563  6.5 6.3 2.0 -8.7 150.5 151.8 23.3
 TYR-563   ALA-564  6.1 6.0 10.7 -9.0 111.0 114.7 8.1
 ALA-564   SER-565  3.1 3.4 15.7 -12.6 174.0 168.7 -54.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  4.1 4.5 10.9 -5.9 101.7 96.0 -15.4
 ILE-639   ALA-640  4.7 4.7 5.7 9.2 99.6 99.1 -21.9
 ALA-640   ASP-641  4.1 3.8 -18.2 -0.7 76.8 66.0 33.8
 ASP-641   PHE-642  7.3 6.8 -36.2 0.7 25.9 35.7 243.7
 PHE-642   GLY-643  7.7 6.4 -41.0 -36.0 69.7 38.1 275.0
 GLY-643   LEU-644  11.3 6.8 36.1 44.1 118.8 82.6 -55.9
 LEU-644   ALA-645  13.0 10.3 154.9 -22.0 139.6 140.8 -986.1
 ALA-645   ARG-646  10.3 13.3 0.1 30.6 156.2 72.3 -112.2
 ARG-646   ASP-647  11.0 16.1 17.4 23.0 131.3 110.9 -271.8
 ASP-647   ILE-648  9.1 19.8 -44.3 51.1 50.8 16.4 -80.3
 ILE-648   HIS-649  11.0 19.2 -83.8 -36.9 45.8 60.9 972.4
 HIS-649   HIS-650  8.5 22.5 -29.5 15.0 35.2 115.8 34.4
 HIS-650   ILE-651  10.8 25.2 116.3 -1.9 83.0 45.7 -758.0
 ILE-651   ASP-652  14.3 23.9 -0.5 -166.7 123.1 124.8 1232.9
 LYS-655   LYS-656  20.7 28.2 28.0 6.7 64.1 15.2 212.8
 LYS-656   THR-657  21.5 28.5 -26.8 -2.5 68.9 104.7 34.6
 THR-657   THR-658  23.9 25.0 -49.7 -54.0 132.9 167.9 -759.2
 THR-658   ASN-659  24.9 23.2 75.6 -39.3 34.3 75.9 135.8
 ASN-659   GLY-660  25.6 21.5 -5.6 -4.0 135.0 66.4 36.6
 GLY-660   ARG-661  24.0 18.9 132.7 120.3 48.2 114.2 -21.5
 ARG-661   LEU-662  21.9 21.2 56.5 53.7 108.0 131.6 -347.6
 LEU-662   PRO-663  20.5 20.7 2.0 -7.6 41.0 59.2 -7.9
 PRO-663   VAL-664  19.0 18.9 -3.6 -18.3 81.4 74.1 23.2
 VAL-664   LYS-665  22.2 22.3 9.4 -12.5 68.1 70.3 -47.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees