DNA Polymerase Eta

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  THR-92   ALA-93  5.2 5.4 5.8 -4.3 122.9 119.5 -15.4  ALA-93   VAL-94  4.8 4.6 3.7 2.2 155.9 158.5 -53.8  VAL-94   PHE-95  5.2 5.1 5.5 -6.8 128.0 122.0 4.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASP-100   PHE-101  13.0 13.2 2.9 -8.9 176.3 176.7 70.3  PHE-101   TRP-102  11.7 11.7 3.4 -11.4 104.0 102.2 21.9  TRP-102   GLN-103  8.7 8.7 -3.7 -2.8 59.9 50.0 50.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-120   VAL-121  4.5 4.3 -0.4 5.6 88.2 86.9 -29.9  VAL-121   GLU-122  6.4 6.1 5.5 -3.5 152.1 151.8 -6.2  GLU-122   ASP-123  5.4 4.9 -6.8 1.8 88.1 91.8 -25.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-125   VAL-126  7.6 7.4 6.1 -2.8 167.3 173.8 -32.4  VAL-126   SER-127  8.4 8.3 0.0 0.8 76.9 71.7 10.7  SER-127   LEU-128  9.9 9.6 -10.9 8.7 18.8 23.8 18.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-387   SER-388  34.6 33.8 5.4 -11.6 117.0 106.4 24.9  SER-388   ARG-389  32.4 32.5 46.7 -46.9 158.0 160.7 -8.5  ARG-389   PRO-390  31.3 30.5 -18.3 -4.0 35.9 45.7 226.7  PRO-390   VAL-391  32.9 32.6 6.4 -0.3 121.9 116.3 20.3  VAL-391   VAL-392  32.0 32.0 7.9 -19.4 134.2 139.0 74.8  VAL-392   LYS-393  29.1 29.1 2.9 -8.9 151.2 150.5 47.0  LYS-393   SER-394  30.6 30.4 2.5 0.2 138.7 134.5 -26.2  SER-394   MET-395  27.4 27.1 17.5 -8.9 69.6 68.3 41.5  MET-395   MET-396  23.6 23.4 6.0 1.0 144.3 146.1 -58.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees