Acid-Sensing Ion Channel

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ALA-428   GLY-429  6.1 6.3 -21.8 12.6 49.6 48.2 24.3  GLY-429   LEU-430  4.2 3.9 -12.8 12.5 46.5 55.2 7.9  LEU-430   LEU-431  1.6 1.3 -14.2 -7.7 44.3 44.8 38.0  LEU-431   GLY-432  5.0 4.8 17.4 1.8 128.4 131.1 -27.3  GLY-432   ASP-433  5.8 5.5 -15.9 -20.7 46.3 30.5 57.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees