Camp-Dependent Protein Kinase (E.C.2.7.1.37)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-31   THR-32  9.5 10.1 51.7 -37.3 87.5 88.8 0.4
 THR-32   PRO-33  9.7 10.3 -14.1 23.3 144.4 143.9 6.2
 PRO-33   SER-34  6.8 7.6 -10.0 6.6 102.2 112.6 -9.9
 SER-34   GLN-35  8.1 9.3 -50.7 46.9 83.3 89.0 -68.7
 GLN-35   ASN-36  8.8 9.3 13.8 -18.1 58.2 52.8 39.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-82   LYS-83  17.7 17.5 -149.4 -157.1 118.3 121.6 158.6
 LYS-83   GLN-84  15.3 16.2 -79.0 -55.6 58.1 126.3 29.0
 GLN-84   ILE-85  12.4 12.7 138.2 -72.9 77.2 109.4 -44.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-104   LYS-105  3.7 3.8 5.0 -21.0 123.1 127.5 95.5
 LYS-105   LEU-106  3.0 3.0 6.6 8.0 112.6 115.9 -0.4
 LEU-106   GLU-107  2.4 2.9 -7.3 2.0 93.6 104.9 -3.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-120   GLU-121  3.2 3.3 -15.8 -7.2 7.7 18.0 143.0
 GLU-121   TYR-122  2.2 2.5 19.5 -43.2 116.0 124.7 46.5
 TYR-122   VAL-123  3.4 2.5 10.8 -24.7 125.1 146.4 17.7
 VAL-123   ALA-124  3.6 1.5 21.7 -17.3 130.5 121.7 49.4
 ALA-124   GLY-125  5.1 3.8 101.6 -76.3 113.0 117.4 -65.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-313   ILE-314  13.4 12.9 -27.4 29.8 70.9 74.1 -8.9
 ILE-314   PRO-315  9.6 9.1 1.7 0.6 84.5 92.7 -49.6
 PRO-315   LYS-316  8.6 8.6 29.8 38.9 59.8 59.2 161.3
 LYS-316   PHE-317  6.3 8.0 12.4 -43.5 104.2 118.4 63.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees