Thermolysin (E.C.3.4.24.27)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-3   THR-4  17.7 17.1 10.9 -7.3 88.7 93.3 -56.3
 THR-4   SER-5  16.6 16.1 9.4 3.1 38.1 33.1 354.5
 SER-5   THR-6  13.5 13.3 -8.5 22.0 125.1 132.3 -23.1
 THR-6   VAL-7  14.7 14.7 -14.9 3.0 31.3 40.1 244.1
 THR-6   VAL-7  14.7 14.7 -14.9 3.0 31.3 40.1 244.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-6   VAL-7  14.7 14.7 -14.9 3.0 31.3 40.1 244.1
 THR-6   VAL-7  14.7 14.7 -14.9 3.0 31.3 40.1 244.1
 VAL-7   GLY-8  13.6 13.6 -16.9 8.0 35.1 36.1 113.5
 GLY-8   VAL-9  14.7 14.8 20.1 -14.9 143.8 145.5 -138.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-30   GLN-31  14.0 14.0 7.8 -7.4 139.7 139.2 -98.7
 GLN-31   ASP-32  12.5 12.4 8.7 -3.0 105.0 102.4 -24.1
 ASP-32   ASN-33  9.0 8.9 -6.5 -2.0 24.1 24.5 224.2
 ASN-33   THR-34  8.3 8.1 2.5 16.0 75.2 80.0 34.4
 ASN-33   THR-34  8.3 8.1 2.5 16.0 75.2 80.0 34.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-33   THR-34  8.3 8.1 2.5 16.0 75.2 80.0 34.4
 ASN-33   THR-34  8.3 8.1 2.5 16.0 75.2 80.0 34.4
 THR-34   ARG-35  5.3 5.6 -21.0 30.9 86.9 99.7 -152.7
 ARG-35   GLY-36  3.2 2.2 66.0 -122.7 61.4 37.1 -783.4
 GLY-36   ASP-37  4.8 2.8 108.6 -27.6 65.1 94.2 227.7
 ASP-37   GLY-38  8.1 6.1 125.3 165.8 139.6 116.4 841.8
 GLY-38   ILE-39  8.5 8.3 -14.4 7.8 30.0 23.9 -75.4
 ILE-39   PHE-40  9.1 9.0 8.9 -6.2 109.4 102.1 332.3
 PHE-40   THR-41  12.7 12.6 14.7 -6.2 159.9 162.2 -298.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-77   GLY-78  6.0 6.0 -6.1 -6.5 43.0 45.1 25.0
 GLY-78   VAL-79  3.0 3.2 19.9 -12.3 79.6 72.6 -2.5
 VAL-79   THR-80  1.6 1.5 10.5 -8.5 104.5 100.6 101.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-96   ASN-97  10.5 10.7 0.1 10.1 103.9 104.2 36.8
 ASN-97   ALA-98  8.1 8.4 -2.8 -16.6 80.9 73.0 173.5
 ALA-98   ALA-99  11.2 11.4 3.1 -8.9 133.0 133.0 155.2
 ALA-99   ILE-100  11.1 10.9 11.6 -2.0 155.2 159.6 -185.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-111   ASN-112  18.6 18.8 3.2 7.8 131.8 135.4 -146.8
 ASN-112   ALA-113  18.2 18.4 -10.5 -14.5 31.1 39.6 537.0
 ALA-113   PHE-114  16.8 16.4 -26.3 9.0 55.4 59.5 28.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-119   MET-120  17.2 16.7 17.3 0.9 158.5 165.2 -575.0
 MET-120   VAL-121  15.6 15.1 -15.0 21.2 57.6 61.4 -73.1
 VAL-121   TYR-122  17.3 17.3 -5.9 0.0 18.3 23.7 42.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-135   GLY-136  7.2 7.0 10.1 -9.6 84.1 82.9 141.5
 GLY-136   ILE-137  6.4 6.4 -3.6 0.8 24.4 28.5 90.6
 ILE-137   ASP-138  5.2 5.4 -8.6 4.0 80.4 82.5 82.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-192   TYR-193  8.5 8.6 -0.8 9.1 44.6 42.7 -96.5
 TYR-193   THR-194  10.8 10.7 -4.5 -3.4 19.0 23.3 172.8
 THR-194   PRO-195  11.1 11.0 -2.8 8.5 73.1 79.0 -106.2
 PRO-195   GLY-196  8.7 8.6 -0.7 -21.5 13.8 29.3 323.4
 GLY-196   ILE-197  9.0 8.0 10.4 14.8 108.3 113.4 -178.4
 ILE-197   SER-198  8.2 7.6 -9.6 -2.6 126.4 129.6 -144.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-199   ASP-200  7.7 7.9 -34.1 8.9 69.9 55.8 25.1
 ASP-200   SER-201  10.5 10.5 -17.3 23.1 11.9 15.3 -30.0
 SER-201   LEU-202  11.8 11.7 0.9 -4.0 100.6 94.9 122.6
 LEU-202   ARG-203  14.9 14.9 4.5 -5.9 94.2 87.8 126.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees