Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-640   ASP-641  6.9 6.0 -13.5 -4.1 97.6 99.7 1.2
 ASP-641   PHE-642  3.9 2.6 -34.1 1.2 98.7 112.8 -6.7
 PHE-642   GLY-643  1.8 2.4 -32.1 -41.1 71.5 50.1 55.2
 GLY-643   LEU-644  2.0 2.6 34.2 29.8 56.6 99.2 37.6
 LEU-644   ALA-645  3.9 3.3 141.8 -16.7 80.0 74.4 48.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.2 11.1 -44.9 16.0 47.8 87.6 26.5
 PRO-663   VAL-664  7.1 7.7 -85.7 -14.6 22.0 47.5 113.2
 VAL-664   LYS-665  8.0 8.3 14.0 -1.1 137.7 136.3 -3.8
 LYS-665   TRP-666  6.6 6.5 -2.8 4.4 93.6 100.8 -2.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees