Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-529   SER-530  16.2 16.2 12.9 -4.9 41.2 33.3 44.7
 SER-530   GLU-531  14.6 14.7 2.4 -6.6 104.1 103.9 18.0
 GLU-531   MET-532  11.5 11.4 -7.3 11.6 66.8 66.0 -17.0
 MET-532   GLU-533  11.3 11.5 -15.9 7.3 130.4 134.0 -11.8
 GLU-533   MET-534  12.4 12.9 0.5 -4.0 54.7 51.6 -19.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-535   LYS-536  7.0 7.5 -8.5 15.2 87.8 88.1 26.2
 LYS-536   MET-537  9.6 10.3 -14.7 18.2 154.7 153.9 31.6
 MET-537   ILE-538  9.6 10.2 -12.5 5.3 107.3 98.8 -19.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-544   ILE-545  2.3 2.4 25.5 -15.7 22.2 21.9 31.5
 ILE-545   ASN-546  1.0 0.9 -16.5 -0.8 88.9 78.2 64.9
 ASN-546   LEU-547  2.7 3.0 13.2 3.3 55.4 54.7 81.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-560   VAL-561  7.8 7.9 3.3 -3.5 56.2 52.2 -21.4
 VAL-561   GLU-562  4.3 4.4 2.6 -1.9 124.2 124.6 2.3
 GLU-562   TYR-563  0.7 1.0 -1.0 -1.3 71.7 67.3 59.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-618   CYS-619  4.3 4.4 -25.4 33.7 123.8 128.6 56.0
 CYS-619   ILE-620  4.9 4.5 -23.3 11.8 89.9 76.2 58.1
 ILE-620   HIS-621  6.6 6.8 -22.4 15.1 156.5 151.1 -57.5
 HIS-621   ARG-622  7.7 7.9 -14.3 28.5 88.7 89.5 -7.6
 ARG-622   ASP-623  11.3 11.6 -27.7 3.8 137.7 120.9 -147.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  5.5 5.5 5.2 15.9 65.0 64.5 56.3
 ALA-640   ASP-641  6.0 6.1 -29.7 -10.3 65.4 52.6 135.1
 ASP-641   PHE-642  8.9 8.1 -14.3 -12.3 24.4 5.1 193.3
 PHE-642   GLY-643  8.4 6.5 -32.6 -34.7 79.6 69.7 59.9
 GLY-643   LEU-644  12.2 8.2 28.9 41.0 152.8 92.1 -336.6
 PRO-663   VAL-664  19.3 20.1 -105.1 -6.2 35.5 13.6 774.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees