Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  11.5 10.9 4.5 2.4 77.1 76.5 -2.1
 ILE-639   ALA-640  7.9 7.3 3.3 12.6 147.2 146.0 -17.2
 ALA-640   ASP-641  5.7 5.2 -25.9 -1.7 100.8 99.8 -1.1
 ASP-641   PHE-642  3.0 1.9 -36.1 10.6 104.7 123.2 -11.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  12.9 13.7 4.5 40.0 116.1 103.1 -3.9
 LEU-662   PRO-663  10.1 12.6 -45.5 19.2 53.6 93.9 27.3
 PRO-663   VAL-664  8.1 9.3 -88.2 -12.9 16.1 47.4 121.1
 VAL-664   LYS-665  9.0 9.5 15.9 -4.4 134.1 136.0 -3.5
 LYS-665   TRP-666  7.9 8.0 3.1 7.0 87.5 80.7 -3.0
 TRP-666   MET-667  4.3 4.6 1.7 9.1 94.2 92.5 2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees