Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-109   GLY-110  3.1 3.3 0.5 4.8 40.3 38.8 50.0  GLY-110   ILE-111  1.3 1.4 -3.3 -1.7 68.5 67.6 49.7  ILE-111   SER-112  4.5 4.6 0.2 -0.3 105.6 106.1 -32.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-192   GLU-193  7.7 7.9 2.3 -0.5 100.2 100.4 33.0  GLU-193   SER-194  4.4 4.7 -0.6 -1.5 122.9 121.1 -30.9  SER-194   THR-195  1.5 1.6 0.1 0.2 32.4 31.7 21.8  THR-195   MET-196  1.6 1.8 -0.2 1.1 142.9 143.3 0.0  MET-196   ASN-197  3.3 3.6 0.0 0.0 104.7 104.1 -13.9  ASN-197   GLU-198  4.1 4.1 0.2 0.3 55.4 56.2 18.2  GLU-198   TYR-199  2.8 2.6 0.3 -1.5 19.6 18.6 -21.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-215   ASP-216  4.9 4.8 -0.6 -1.7 54.8 54.6 30.1  ASP-216   SER-217  1.7 1.7 -0.1 -0.4 119.3 119.8 8.1  SER-217   LYS-218  2.4 2.5 -0.9 -7.6 94.1 90.8 -83.2  LYS-218   GLY-219  5.7 5.9 5.9 2.2 50.2 40.2 116.7  GLY-219   TYR-220  8.5 8.6 4.6 1.7 60.7 62.7 10.4  TYR-220   GLY-221  10.9 11.0 0.2 1.7 99.2 98.2 -23.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-251   ASN-252  9.5 9.3 2.0 0.5 129.6 125.3 -37.6  ASN-252   LYS-253  10.2 10.0 0.2 -0.9 160.1 164.4 19.0  LYS-253   TRP-254  10.4 10.2 -0.7 0.2 78.3 77.8 10.9  TRP-254   TRP-255  7.3 7.2 -0.3 -0.1 102.1 103.7 -10.8  TRP-255   TYR-256  4.9 4.7 -2.2 -2.0 56.8 61.1 46.7  TYR-256   ASP-257  7.3 7.0 0.9 3.1 155.9 153.2 -78.3  ASP-257   LYS-258  9.1 9.1 -0.2 0.8 49.3 43.5 30.5  LYS-258   GLY-259  6.0 6.0 0.5 2.8 81.6 84.1 75.4  GLY-259   GLU-260  4.4 4.5 -3.2 2.1 35.1 33.8 16.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees