Potassium/sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 11

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-234   ILE-235  30.2 31.4 16.7 -33.5 69.4 79.5 -50.3
 ILE-235   PHE-236  33.1 33.9 17.7 -13.1 47.1 18.8 25.0
 PHE-236   LEU-237  32.8 33.6 13.3 -6.0 113.1 85.4 28.4
 LEU-237   ILE-238  33.1 34.8 8.7 -12.1 110.2 105.5 1.5
 ILE-238   VAL-239  36.0 37.8 7.3 -11.0 44.5 43.5 -24.3
 VAL-239   GLU-240  37.7 38.4 20.2 -98.8 73.2 37.9 -213.8
 ARG-252   ALA-253  34.8 27.3 8.2 4.4 140.1 94.0 -54.7
 ALA-253   LEU-254  33.7 29.2 -2.5 0.8 93.5 52.6 -11.9
 LEU-254   ARG-255  30.5 27.2 0.5 -3.1 51.8 65.3 -23.5
 ARG-255   ILE-256  29.9 23.9 18.0 -14.6 113.1 44.9 31.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-263   SER-264  24.7 22.4 55.6 -10.1 35.2 38.5 180.9
 SER-264   LEU-265  23.1 22.3 36.3 -10.6 100.0 98.0 -6.6
 LEU-265   LEU-266  19.8 20.1 -14.1 1.6 67.7 71.2 29.2
 LEU-266   ARG-267  22.0 23.3 -16.2 11.5 139.0 138.6 -49.9
 ARG-267   LEU-268  21.6 24.5 -37.1 4.5 92.6 98.8 -33.6
 LEU-268   LEU-269  18.3 21.6 -14.2 -2.9 68.6 42.1 62.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-291   ALA-292  27.0 22.9 167.4 15.8 149.9 74.7 -693.7
 ALA-292   SER-293  26.2 20.7 -153.7 -5.7 48.1 45.3 567.9
 SER-293   ALA-294  25.4 21.4 3.3 -4.6 113.7 138.1 -19.3
 ALA-294   VAL-295  23.2 20.0 3.6 -1.7 54.2 73.7 -7.6
 VAL-295   VAL-296  21.2 16.9 1.0 -4.6 86.2 91.9 21.2
 VAL-296   ARG-297  20.8 16.4 4.2 -4.4 140.1 158.6 20.7
 ARG-297   ILE-298  19.7 16.9 4.4 -6.7 91.5 116.2 -18.2
 ILE-298   PHE-299  17.0 14.4 10.2 -8.4 48.6 64.5 -13.7
 PHE-299   ASN-300  15.7 11.8 8.0 -4.3 108.8 110.2 17.3
 ASN-300   LEU-301  15.9 12.9 2.1 -0.4 128.6 153.5 -6.2
 LEU-301   ILE-302  13.7 11.8 -2.8 -4.2 114.1 94.7 -16.9
 ILE-302   GLY-303  11.1 8.5 9.8 -6.1 71.4 72.3 22.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees