Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-207   ASP-208  3.4 3.1 11.3 -13.8 132.0 132.1 37.1
 ASP-208   THR-209  4.0 3.5 -9.7 9.9 90.1 88.2 -27.4
 THR-209   LEU-210  2.7 3.0 -18.1 21.7 36.5 32.6 -22.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-234   ASN-235  16.3 16.9 38.0 -32.3 95.3 105.4 21.9
 ASN-235   TYR-236  12.7 13.4 -0.9 -1.8 145.4 142.2 -32.0
 TYR-236   GLY-237  11.4 11.9 15.3 3.3 65.5 67.8 53.3
 GLY-237   GLU-238  12.9 13.3 -19.6 18.1 56.5 56.0 -9.0
 GLU-238   SER-239  13.2 13.0 -11.6 24.5 75.6 86.0 -0.5
 SER-239   GLY-240  9.5 9.2 -28.5 11.3 144.0 138.5 -86.0
 GLY-240   MET-241  8.4 8.1 -12.2 15.1 105.9 97.9 28.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-340   LYS-341  5.2 5.2 -28.0 45.0 77.2 84.5 -3.4
 LYS-341   LEU-342  6.8 7.2 29.6 -27.7 115.3 133.2 -58.8
 LEU-342   GLN-343  7.5 7.9 -1.5 -4.4 131.5 118.0 -47.8
 GLN-343   SER-344  9.1 8.9 -35.3 -37.7 69.4 65.6 184.5
 SER-344   PRO-345  12.9 12.6 34.4 -13.4 53.4 45.0 105.3
 PRO-345   GLU-346  15.0 15.3 29.2 -5.5 96.7 108.7 -49.0
 GLU-346   VAL-347  18.4 18.7 4.9 31.1 110.2 99.2 -101.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-477   ARG-478  5.7 5.4 -28.3 15.8 12.2 13.7 97.6
 ARG-478   TYR-479  6.3 6.4 -3.6 9.8 65.0 64.7 -22.9
 TYR-479   ASP-480  4.2 3.9 12.1 -27.1 173.1 176.0 120.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees