Thermolysin

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-86   VAL-87  5.4 5.4 0.8 0.1 94.5 94.1 -50.2
 VAL-87   HIS-88  8.2 8.2 -0.9 0.8 43.4 43.1 -86.7
 HIS-88   ASN-89  8.4 8.4 -2.8 2.8 35.2 35.0 44.4
 ASN-89   ARG-90  5.5 5.5 -1.2 1.3 99.1 98.6 -46.6
 ASN-89   ARG-90  5.5 5.5 -1.2 1.3 99.1 98.6 -46.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-89   ARG-90  5.5 5.5 -1.2 1.3 99.1 98.6 -46.6
 ASN-89   ARG-90  5.5 5.5 -1.2 1.3 99.1 98.6 -46.6
 ARG-90   LEU-91  5.6 5.6 -0.2 -0.4 70.6 70.9 41.2
 LEU-91   SER-92  4.3 4.3 -0.9 0.9 63.6 63.6 17.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-123   ASP-124  17.1 17.1 1.4 0.0 49.7 49.1 150.3
 ASP-124   GLY-125  15.5 15.5 -0.4 0.9 132.6 132.1 148.8
 GLY-125   ASP-126  16.1 16.1 0.1 -0.8 32.8 31.9 0.2
 ASP-126   GLY-127  17.6 17.6 0.0 -1.4 44.0 43.4 -143.8
 GLY-127   GLN-128  14.3 14.3 1.3 -0.6 56.7 57.4 13.3
 GLN-128   THR-129  15.2 15.3 -0.9 0.2 51.5 51.1 38.1
 THR-129   PHE-130  16.4 16.4 -2.8 1.7 133.8 132.9 -124.5
 THR-129   PHE-130  16.4 16.4 -2.8 1.7 133.8 132.9 -124.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-129   PHE-130  16.4 16.4 -2.8 1.7 133.8 132.9 -124.5
 THR-129   PHE-130  16.4 16.4 -2.8 1.7 133.8 132.9 -124.5
 PHE-130   ILE-131  13.9 14.0 -0.9 2.2 78.4 78.0 144.9
 ILE-131   PRO-132  11.4 11.5 2.6 -1.4 14.6 15.9 111.9
 PRO-132   LEU-133  11.7 11.7 0.5 1.9 50.7 49.3 252.8
 LEU-133   SER-134  11.5 11.6 -3.1 -0.8 134.0 132.6 -445.4
 SER-134   GLY-135  9.2 9.3 0.2 1.4 111.7 112.0 -85.9
 GLY-135   GLY-136  6.4 6.5 -1.5 -0.5 102.8 103.4 -121.9
 GLY-136   ILE-137  7.0 6.9 4.5 -1.2 10.8 10.3 453.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-141   HIS-142  8.8 8.8 0.0 -0.1 101.2 100.8 -105.5
 HIS-142   GLU-143  12.5 12.5 4.1 -3.2 118.3 117.9 45.7
 GLU-143   LEU-144  13.5 13.4 0.6 -0.5 158.8 159.9 -26.7
 LEU-144   THR-145  11.3 11.2 -0.2 -1.3 49.9 51.6 153.3
 THR-145   HIS-146  12.5 12.5 -0.6 0.9 72.2 74.7 7.8
 HIS-146   ALA-147  15.9 15.9 -2.6 -0.6 33.7 32.5 377.2
 ALA-147   VAL-148  14.6 14.8 0.4 0.1 142.6 142.0 -76.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees