Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-208   THR-209  6.2 5.7 -36.5 24.0 85.0 83.7 13.1
 THR-209   LEU-210  3.9 4.0 -8.2 -0.2 59.6 66.9 0.1
 LEU-210   GLN-211  1.4 1.0 -26.6 9.2 12.6 18.4 220.5
 GLN-211   ALA-212  3.2 3.1 5.4 -15.2 110.8 126.4 19.5
 ALA-212   ARG-213  3.9 3.5 3.6 14.2 97.6 93.3 14.4
 ARG-213   ALA-214  2.6 2.7 18.1 -17.0 146.1 141.1 -14.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 HIS-231   THR-232  14.4 14.3 -15.8 22.9 85.3 80.3 33.8
 THR-232   GLU-233  16.9 16.7 -13.0 -1.5 25.9 31.6 125.4
 GLU-233   GLY-234  19.4 19.4 -12.0 -3.8 48.9 42.4 79.6
 GLY-234   ASN-235  18.7 19.1 33.4 -17.3 63.6 67.2 129.1
 GLY-234   ASN-235  18.7 19.1 33.4 -17.3 63.6 67.2 129.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-234   ASN-235  18.7 19.1 33.4 -17.3 63.6 67.2 129.1
 GLY-234   ASN-235  18.7 19.1 33.4 -17.3 63.6 67.2 129.1
 ASN-235   TYR-236  15.8 16.5 -3.4 -6.2 57.7 64.6 6.2
 TYR-236   GLY-237  13.5 13.9 11.2 -13.2 126.6 117.0 27.2
 GLY-237   GLU-238  13.6 13.2 -9.1 15.6 114.0 124.2 67.0
 GLU-238   SER-239  14.6 14.7 11.0 -7.1 54.1 44.4 -13.6
 SER-239   GLY-240  11.8 12.1 -5.9 -6.6 57.0 68.9 63.5
 GLY-240   MET-241  9.2 9.0 2.6 9.6 119.1 114.4 -72.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-316   SER-317  7.2 7.4 -24.5 8.8 38.0 39.3 93.6
 SER-317   ASP-318  7.5 7.4 -4.1 11.1 98.2 90.5 12.1
 ASP-318   GLY-319  9.9 9.8 -7.6 6.9 96.8 94.3 40.3
 GLY-319   TRP-320  12.8 12.5 -25.6 26.5 161.6 155.7 3.1
 TRP-320   ALA-321  12.1 12.3 0.7 16.6 87.4 91.2 -29.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ILE-340   LYS-341  6.4 6.3 -38.3 41.3 70.4 72.0 50.9
 LYS-341   LEU-342  9.6 9.8 -29.8 9.2 37.3 29.9 172.0
 LEU-342   GLN-343  10.8 10.3 -13.6 -5.1 106.3 92.3 -76.4
 GLN-343   SER-344  13.2 12.9 -42.0 24.1 60.8 41.5 72.2
 SER-344   PRO-345  16.7 15.9 24.2 -14.8 80.0 64.3 68.6
 PRO-345   GLU-346  19.3 18.9 44.1 -29.2 103.5 113.0 -61.8
 GLU-346   VAL-347  22.8 22.4 18.4 -13.8 137.8 135.6 -4.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-477   ARG-478  7.2 7.4 2.6 -2.4 142.4 134.8 -26.4
 ARG-478   TYR-479  9.4 9.4 7.5 -8.5 135.4 143.3 69.6
 TYR-479   ASP-480  8.4 8.1 -17.2 3.2 27.6 25.1 87.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-498   THR-499  9.6 9.4 -18.0 3.5 28.0 26.2 124.5
 THR-499   TRP-500  9.3 9.2 -7.2 2.6 56.7 47.7 -54.3
 TRP-500   HIS-501  7.3 7.3 -5.2 -7.3 37.1 35.8 70.3
 HIS-501   GLU-502  10.0 9.8 -8.7 10.0 35.2 32.6 7.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees