Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-713   LYS-714  7.0 7.0 -7.7 -9.7 46.3 47.2 61.2
 LYS-714   GLY-715  5.8 5.7 -2.1 -4.2 71.3 71.3 5.5
 GLY-715   PRO-716  2.1 1.9 22.8 -30.6 95.7 107.5 4.8
 PRO-716   GLU-717  2.0 2.5 -98.5 97.2 37.4 28.6 27.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-816   LEU-817  10.9 10.5 -17.8 23.7 53.5 51.4 43.2
 LEU-817   PRO-818  7.8 7.2 -40.5 3.4 53.8 66.5 102.6
 PRO-818   ALA-819  6.4 6.0 -15.0 -5.0 111.4 103.0 -15.5
 ALA-819   VAL-820  5.4 3.8 6.0 7.9 100.6 132.4 -34.8
 VAL-820   SER-821  2.1 2.3 -31.2 -12.1 76.9 64.5 38.5
 SER-821   GLU-822  2.3 2.7 -3.0 11.3 20.4 29.9 -20.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees