Metabotropic Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-493   PRO-494  14.7 14.8 -14.3 -7.7 41.4 51.6 73.4  PRO-494   LEU-495  11.6 11.7 17.5 -17.2 137.6 148.9 -3.1  LEU-495   PRO-496  11.1 10.7 -10.7 11.8 98.6 95.4 19.5  PRO-496   ALA-497  10.2 9.7 118.4 -70.6 103.7 104.2 -103.3  ALA-497   SER-498  6.6 6.0 27.6 -48.4 76.5 121.5 65.5  SER-498   ARG-499  5.4 4.7 -48.6 24.7 76.5 74.9 43.8  ARG-499   CYS-500  2.6 1.6 9.5 -4.4 55.2 70.6 18.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees