Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-107   SER-108  8.0 8.0 -2.3 -18.0 44.3 38.7 285.7  SER-108   LEU-109  6.9 6.8 -8.0 3.1 111.9 99.2 -131.9  LEU-109   GLY-110  5.6 5.7 19.2 -21.1 136.6 131.4 15.7  GLY-110   ILE-111  5.8 5.7 -4.8 -1.9 118.6 116.9 -78.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  SER-217   LYS-218  3.5 3.1 14.3 -8.2 109.0 114.4 -17.8  LYS-218   GLY-219  1.9 1.6 -15.6 13.1 40.5 43.7 132.9  GLY-219   TYR-220  3.7 3.7 -1.3 -6.9 37.8 32.2 86.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-250   LYS-251  15.3 15.2 4.1 -6.1 107.8 104.7 59.6  LYS-251   ASN-252  13.9 13.8 5.6 4.1 82.4 79.3 90.2  ASN-252   LYS-253  17.4 17.5 -5.4 1.2 162.4 167.1 -20.9  LYS-253   TRP-254  17.5 17.4 5.2 -7.8 72.8 67.7 -61.9  TRP-254   TRP-255  14.3 14.3 5.1 0.8 118.2 118.2 -239.1  TRP-255   TYR-256  15.1 15.1 -66.0 -52.3 87.4 88.7 318.4  TYR-256   ASP-257  18.8 18.9 -169.8 32.9 100.2 134.2 2364.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees