Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  8.8 8.4 14.3 3.9 147.6 145.7 -20.5
 ALA-640   ASP-641  6.6 6.1 -11.9 -13.7 100.0 100.6 -5.1
 ASP-641   PHE-642  3.6 2.8 -29.8 -4.2 102.3 119.3 -9.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  12.2 13.2 9.2 40.0 115.3 100.9 -16.6
 LEU-662   PRO-663  9.4 11.8 -29.7 19.4 51.5 86.0 11.3
 PRO-663   VAL-664  7.4 8.3 -91.1 -15.1 18.5 33.9 120.3
 VAL-664   LYS-665  8.3 8.7 15.7 -9.4 135.2 135.1 -0.4
 LYS-665   TRP-666  7.1 7.4 -2.1 6.4 93.4 95.7 -2.1
 TRP-666   MET-667  3.6 4.1 -8.0 16.2 88.2 88.4 1.1
 MET-667   ALA-668  4.4 4.3 -3.0 3.8 27.3 28.2 -0.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees