Vitamin D Hydroxylase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-145   PRO-146  5.9 6.9 -1.2 3.5 155.1 151.3 36.7
 PRO-146   VAL-147  4.6 5.4 2.7 -14.9 54.3 54.3 7.3
 VAL-147   GLN-148  7.5 7.6 12.7 6.6 104.8 116.4 0.2
 GLN-148   VAL-149  8.1 8.1 -0.6 -9.0 100.8 93.5 -8.6
 VAL-149   ILE-150  5.0 4.7 6.8 8.0 14.4 23.1 53.5
 ILE-150   CYS-151  5.1 5.1 -3.1 3.0 106.6 94.0 -12.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-211   ALA-212  14.3 15.3 19.1 -18.2 109.4 97.9 21.7
 ALA-212   VAL-213  17.2 17.7 6.8 20.9 129.3 124.8 -75.1
 VAL-213   SER-214  15.4 15.9 174.4 -106.0 157.5 156.3 -426.6
 SER-214   ASP-215  13.9 18.2 155.2 -17.9 119.4 91.6 1066.9
 ASP-215   MET-216  17.4 19.2 -145.1 7.3 66.9 60.4 -392.6
 MET-216   ASP-217  18.9 22.8 14.0 68.1 140.4 160.6 -408.8
 ASP-217   GLY-218  16.5 21.6 -76.0 137.9 79.8 93.9 -62.8
 GLY-218   ASP-219  13.6 20.6 29.5 16.5 107.2 86.9 -26.7
 ASP-219   ARG-220  12.4 16.8 177.3 -86.2 38.0 33.9 493.4
 ARG-220   LEU-221  12.4 14.7 -148.9 71.8 114.5 76.8 -33.1
 LEU-221   SER-222  10.1 11.4 20.7 10.6 119.6 116.1 -52.2
 SER-222   GLN-223  9.6 11.6 2.6 -3.6 50.9 52.2 3.0
 GLN-223   GLU-224  10.8 12.4 5.3 1.1 79.7 88.5 34.4
 GLU-224   GLU-225  7.9 9.3 -1.8 -2.8 127.4 123.4 -32.8
 GLU-225   LEU-226  5.5 7.2 3.2 -1.4 19.5 11.0 20.2
 LEU-226   VAL-227  7.9 8.9 -2.5 -3.0 113.9 113.0 -21.1
 VAL-227   ALA-228  8.2 8.6 0.0 6.6 76.6 91.2 5.4
 ALA-228   MET-229  4.8 5.1 -7.9 -0.6 142.6 140.2 -28.7
 MET-229   ALA-230  3.8 4.1 3.8 -7.8 33.6 29.4 -1.9
 ALA-230   MET-231  6.3 5.9 2.9 0.4 77.7 84.4 13.1
 MET-231   LEU-232  6.3 5.8 6.4 -2.3 67.0 80.6 8.3
 LEU-232   LEU-233  3.2 2.4 5.2 4.5 14.0 13.7 58.3
 LEU-233   LEU-234  2.3 1.6 -5.7 7.1 126.7 124.3 10.2
 LEU-234   ILE-235  5.8 4.9 -10.4 0.2 99.3 83.6 -35.2
 ILE-235   ALA-236  6.8 6.1 0.7 -14.7 53.8 69.4 -47.6
 ALA-236   GLY-237  4.5 4.7 11.4 -28.2 17.2 4.7 -69.1
 GLY-237   HIS-238  4.3 3.7 6.5 15.5 65.0 50.9 38.2
 HIS-238   GLU-239  8.1 6.7 -49.1 59.2 93.7 104.7 40.9
 HIS-238   GLU-239  8.1 6.7 -49.1 59.2 93.7 104.7 40.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-238   GLU-239  8.1 6.7 -49.1 59.2 93.7 104.7 40.9
 HIS-238   GLU-239  8.1 6.7 -49.1 59.2 93.7 104.7 40.9
 GLU-239   THR-240  9.5 9.9 -44.1 64.6 106.4 110.2 61.7
 THR-240   THR-241  8.5 9.1 15.7 -10.1 10.3 12.8 6.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees