Hexokinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-110   VAL-111  2.1 2.3 5.8 -8.1 51.9 49.6 -8.4
 VAL-111   VAL-112  1.5 1.3 -3.3 2.0 61.7 62.3 11.1
 VAL-112   ILE-113  5.1 5.0 -2.1 -4.2 108.4 111.5 -32.3
 ILE-113   ALA-114  8.0 7.8 -20.4 12.3 78.7 74.5 83.8
 ALA-114   GLY-115  11.4 11.0 12.8 -5.7 66.7 61.6 58.3
 GLY-115   THR-116  14.1 14.1 11.8 -7.5 128.4 129.1 -24.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-120   GLU-121  4.3 4.3 3.8 15.6 62.6 63.7 85.5
 GLU-121   GLY-122  1.8 1.8 3.5 -8.8 119.8 110.5 20.8
 GLY-122   TYR-123  2.6 2.5 -4.3 -9.0 113.7 111.4 -18.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-128   LEU-129  5.8 5.8 0.7 2.6 125.2 123.5 12.2
 LEU-129   ARG-130  2.3 2.4 10.0 -2.2 64.2 66.3 19.3
 ARG-130   VAL-131  1.7 1.6 -6.2 -4.3 60.0 67.3 45.3
 VAL-131   GLY-132  4.8 4.8 -8.1 5.9 107.0 108.5 16.7
 GLY-132   GLY-133  8.1 8.1 -0.4 3.9 94.0 91.7 14.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-272   GLY-273  10.8 10.8 -10.0 7.2 80.7 91.8 -20.3
 GLY-273   LYS-274  7.3 7.1 2.5 -44.4 121.3 113.2 70.5
 LYS-274   ARG-275  5.7 5.9 51.5 -17.6 59.3 73.2 48.7
 ARG-275   SER-276  4.3 4.2 19.4 -16.2 12.8 15.8 17.4
 SER-276   PRO-277  5.9 5.4 2.4 -4.9 56.4 54.2 -18.8
 LEU-272   GLY-273  4.2 3.7 -10.0 7.2 90.4 98.0 -37.7
 GLY-273   LYS-274  2.5 2.7 2.5 -44.4 142.1 136.5 264.8
 LYS-274   ARG-275  5.2 5.7 51.5 -17.6 75.4 77.3 24.0
 ARG-275   SER-276  8.4 8.9 19.4 -16.2 44.1 47.6 -0.5
 LEU-272   GLY-273  10.8 10.8 -10.0 7.2 80.7 91.8 -20.3
 GLY-273   LYS-274  7.3 7.1 2.5 -44.4 121.3 113.2 70.5
 LYS-274   ARG-275  5.7 5.9 51.5 -17.6 59.3 73.2 48.7
 ARG-275   SER-276  4.3 4.2 19.4 -16.2 12.8 15.8 17.4
 SER-276   PRO-277  5.9 5.4 2.4 -4.9 56.4 54.2 -18.8
 SER-270   ASP-271  6.3 6.2 5.5 -8.9 140.7 138.3 21.2
 ASP-271   LEU-272  3.1 3.0 7.6 -2.5 79.5 75.8 -3.0
 LEU-272   GLY-273  4.2 3.7 -10.0 7.2 90.4 98.0 -37.7
 GLY-273   LYS-274  2.5 2.7 2.5 -44.4 142.1 136.5 264.8
 LYS-274   ARG-275  5.2 5.7 51.5 -17.6 75.4 77.3 24.0
 ARG-275   SER-276  8.4 8.9 19.4 -16.2 44.1 47.6 -0.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees