Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  8.7 8.0 2.5 9.3 145.1 142.1 -12.6
 ALA-640   ASP-641  6.5 5.8 -29.0 -4.1 101.8 101.2 -6.1
 ASP-641   PHE-642  3.6 2.3 -20.9 -1.5 100.8 123.9 -8.7
 PHE-642   GLY-643  1.3 2.4 -44.9 -37.2 75.7 65.0 43.5
 GLY-643   LEU-644  2.6 3.5 45.5 23.4 53.1 101.0 50.9
 LEU-644   ALA-645  4.2 3.9 156.7 -23.6 81.2 65.5 69.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.1 11.2 -44.5 20.2 51.1 98.8 20.9
 PRO-663   VAL-664  7.0 8.1 -88.0 -21.6 20.9 52.0 114.6
 VAL-664   LYS-665  7.7 8.1 18.6 -8.7 133.6 135.3 -1.8
 LYS-665   TRP-666  6.3 6.4 13.4 -3.9 83.4 74.6 -2.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees