Importin Beta Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-547   GLN-548  9.6 11.1 3.9 8.9 36.5 28.7 48.0
 GLN-548   LYS-549  12.1 13.5 -15.7 14.1 144.0 140.2 -5.4
 LYS-549   THR-550  10.2 11.7 8.0 -3.3 83.9 82.6 1.2
 THR-550   THR-551  7.1 8.6 -8.2 11.5 69.0 62.0 -3.2
 THR-550   THR-551  7.1 8.6 -8.2 11.5 69.0 62.0 -3.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-550   THR-551  7.1 8.6 -8.2 11.5 69.0 62.0 -3.2
 THR-550   THR-551  7.1 8.6 -8.2 11.5 69.0 62.0 -3.2
 THR-551   LEU-552  9.6 10.8 -8.8 7.6 5.1 2.6 3.6
 LEU-552   VAL-553  10.0 11.2 -17.1 11.8 66.3 72.3 27.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-561   LEU-562  10.9 8.8 18.7 -19.9 50.0 64.2 -6.5
 LEU-562   GLN-563  13.7 12.1 12.4 6.6 24.3 10.8 88.6
 GLN-563   MET-564  11.8 10.8 -67.2 55.9 86.4 95.3 -14.4
 MET-564   GLU-565  12.0 9.5 -28.7 12.3 98.3 85.6 -1.1
 GLU-565   SER-566  15.5 13.3 -41.0 5.1 137.8 145.7 -126.1
 SER-566   HIS-567  14.0 14.0 98.3 -76.9 108.2 73.8 47.1
 HIS-567   ILE-568  14.1 13.0 39.6 -16.8 114.1 122.6 -33.1
 ILE-568   GLN-569  17.3 16.0 35.5 -15.8 55.5 58.5 50.0
 GLN-569   SER-570  19.8 18.3 21.7 -19.7 122.9 124.3 -6.5
 GLN-569   SER-570  19.8 18.3 21.7 -19.7 122.9 124.3 -6.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-569   SER-570  19.8 18.3 21.7 -19.7 122.9 124.3 -6.5
 GLN-569   SER-570  19.8 18.3 21.7 -19.7 122.9 124.3 -6.5
 SER-570   THR-571  22.5 20.5 -9.7 3.9 46.0 47.3 23.8
 THR-571   SER-572  23.9 22.2 7.5 4.9 143.6 139.9 -21.1
 SER-572   ASP-573  22.0 20.0 -40.8 30.4 100.3 96.3 14.5
 ASP-573   ARG-574  18.8 16.8 2.6 9.5 103.5 108.3 0.6
 ARG-574   ILE-575  20.0 18.2 -46.7 36.8 7.9 15.4 41.9
 ILE-575   GLN-576  20.3 18.5 8.7 12.0 112.3 103.7 -34.6
 ILE-575   GLN-576  20.3 18.5 8.7 12.0 112.3 103.7 -34.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-575   GLN-576  20.3 18.5 8.7 12.0 112.3 103.7 -34.6
 ILE-575   GLN-576  20.3 18.5 8.7 12.0 112.3 103.7 -34.6
 GLN-576   PHE-577  16.9 15.0 -37.8 26.1 108.6 96.3 -2.4
 PHE-577   ASN-578  15.5 13.7 -14.6 10.2 51.0 44.7 5.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-591   LEU-592  11.7 11.5 -7.8 6.0 96.8 94.4 -6.6
 LEU-592   ARG-593  15.5 15.3 -13.1 27.6 158.6 155.4 65.1
 ARG-593   LYS-594  15.8 16.1 -26.9 25.7 112.4 113.5 -12.8
 LYS-594   VAL-595  13.9 14.7 4.1 -1.5 118.1 118.8 -15.4
 VAL-595   GLN-596  16.0 17.0 3.9 -10.1 74.9 76.3 -18.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees