Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  11.8 11.3 7.1 5.6 75.4 73.2 -2.6
 ILE-639   ALA-640  8.2 7.7 4.8 15.9 145.4 143.4 -19.9
 ALA-640   ASP-641  6.1 5.9 -34.1 9.8 102.6 101.8 6.9
 ASP-641   PHE-642  3.5 2.9 -37.0 -1.8 105.0 116.7 -17.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  12.8 14.5 24.7 51.8 114.4 77.6 -21.5
 LEU-662   PRO-663  9.9 12.6 -21.8 11.0 54.5 95.4 14.9
 PRO-663   VAL-664  8.0 9.1 -87.9 -7.3 16.4 49.8 112.5
 VAL-664   LYS-665  8.7 8.8 18.6 -4.8 132.4 136.9 -7.7
 LYS-665   TRP-666  7.8 7.7 3.9 6.0 85.8 81.4 -3.5
 TRP-666   MET-667  4.3 4.4 -0.6 -0.1 85.8 88.8 1.3
 MET-667   ALA-668  4.5 4.3 -6.4 11.1 25.1 33.0 -4.5
 ALA-668   PRO-669  4.8 4.2 -0.4 -19.7 74.8 70.3 6.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees