Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-68   GLY-69  9.9 10.0 -14.9 10.1 110.2 110.6 -97.5  GLY-69   PRO-70  6.5 6.6 -6.7 -8.3 102.4 99.2 36.8  PRO-70   GLU-71  7.1 7.3 28.1 -27.8 33.4 28.5 47.3  GLU-71   ILE-72  10.1 9.9 0.0 10.2 85.2 86.3 152.0 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-162   VAL-163  8.3 7.5 -5.7 19.9 158.2 149.2 206.3  VAL-163   SER-164  10.2 9.6 38.6 -38.7 35.6 37.8 -90.8  SER-164   ILE-165  9.3 9.2 28.3 -26.2 43.8 49.4 -42.3  ILE-165   ALA-166  9.2 9.1 11.9 8.4 154.1 158.7 -259.2  ILE-165   ALA-166  9.2 9.1 11.9 8.4 154.1 158.7 -259.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ILE-165   ALA-166  9.2 9.1 11.9 8.4 154.1 158.7 -259.2  ILE-165   ALA-166  9.2 9.1 11.9 8.4 154.1 158.7 -259.2  ALA-166   LEU-167  9.9 10.3 -8.7 -14.6 42.1 43.0 262.9  LEU-167   PRO-168  8.3 8.4 16.5 8.0 118.1 119.6 -197.7  PRO-168   ALA-169  5.7 6.2 24.3 -37.4 74.6 68.3 94.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees