Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-309   ARG-310  5.7 5.7 2.5 1.5 74.9 57.1 0.6
 ARG-310   LYS-311  2.5 2.1 17.7 81.0 29.9 41.1 73.3
 LYS-311   VAL-312  1.4 1.9 -8.7 10.4 102.9 77.4 0.7
 VAL-312   CYS-313  3.8 5.1 -15.3 32.9 169.2 150.0 14.6
 CYS-313   ASN-314  5.5 6.6 -23.3 -13.0 96.9 91.9 -2.8
 ASN-314   GLY-315  8.7 10.0 -11.5 2.9 103.1 105.5 -2.8

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees