Large T Antigen

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLN-354   LEU-355  4.4 4.5 -2.0 5.0 129.9 131.5 32.6  LEU-355   THR-356  3.0 3.1 -4.2 -1.4 86.2 83.3 47.8  THR-356   ARG-357  5.0 4.5 -2.1 6.5 144.4 147.2 15.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLU-510   LYS-511  25.4 26.2 -19.0 -27.9 22.3 30.3 340.6  LYS-511   LYS-512  26.1 26.1 116.7 -7.2 79.0 73.0 195.6  LYS-512   HIS-513  29.4 28.1 173.9 145.3 51.0 57.9 -407.7  HIS-513   LEU-514  29.7 30.8 -0.9 -44.6 63.8 171.8 -181.9  LEU-514   ASN-515  26.8 28.9 -103.6 42.4 114.3 96.4 609.5  ASN-515   LYS-516  23.5 25.9 -22.3 26.2 111.1 89.5 57.5  LYS-516   ARG-517  23.0 22.7 77.4 122.9 73.5 71.5 -318.7  ARG-517   THR-518  20.0 19.4 3.1 -17.0 73.8 66.3 -113.0  THR-518   GLN-519  19.2 18.9 -7.7 3.5 71.8 72.3 -35.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees