Human Immunodeficiency Virus Type 1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-241   GLN-242  9.3 11.3 -20.8 0.1 153.8 162.8 -80.9
 GLN-242   PRO-243  9.4 9.9 143.3 -20.9 66.5 46.4 217.8
 PRO-243   ILE-244  12.1 12.5 -5.6 -65.4 81.8 67.0 103.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-309   LEU-310  21.7 21.3 25.3 -16.8 98.0 90.9 -8.2
 LEU-310   LYS-311  18.6 19.1 -39.7 26.5 40.9 44.8 29.7
 LYS-311   GLU-312  17.9 17.6 -44.0 5.7 111.9 109.0 -34.2
 GLU-312   PRO-313  17.1 16.4 -6.0 27.0 112.2 157.0 28.5
 PRO-313   VAL-314  13.3 13.7 28.6 -27.9 24.9 34.8 -4.5
 VAL-314   HIS-315  12.4 13.9 -4.2 69.4 100.7 121.7 94.9
 HIS-315   GLY-316  9.9 11.2 -7.0 49.2 143.8 160.8 131.9
 GLY-316   VAL-317  9.5 10.3 -70.5 38.2 108.1 129.5 -49.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees