Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
7.1
6.7
-5.1
-3.4
41.8
50.3
35.8
LYS-114
GLY-115
7.1
6.6
-17.7
-4.9
78.5
76.7
27.1
GLY-115
PRO-116
3.6
3.3
21.0
-5.8
96.2
113.6
-2.8
PRO-116
GLU-117
4.3
4.8
-85.7
85.4
19.1
27.0
-9.6
GLU-117
ILE-118
6.7
6.4
4.0
-26.3
91.3
97.1
75.6
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-215
ASP-216
10.3
10.0
-19.4
21.3
16.9
14.6
-38.4
ASP-216
LEU-217
10.9
11.3
-20.5
4.0
53.1
48.8
45.1
LEU-217
PRO-218
8.5
8.8
-12.2
-14.2
47.3
61.6
60.1
PRO-218
ALA-219
6.5
6.4
0.0
-15.9
67.6
69.7
-11.7
ALA-219
VAL-220
3.8
3.1
11.1
-1.4
89.2
128.6
-15.8
VAL-220
SER-221
1.6
2.0
-44.0
-0.9
82.0
64.3
50.7
SER-221
GLU-222
5.2
5.4
-1.2
18.0
30.4
32.5
-39.5
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees