B-Raf Proto-Oncogene Serine/threonine-Protein Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-482   LYS-483  10.4 10.4 15.4 -2.8 119.9 119.5 -29.4
 LYS-483   MET-484  9.1 9.0 -2.4 -29.2 53.5 48.3 31.9
 MET-484   LEU-485  7.0 7.3 43.6 -31.0 109.7 138.9 -47.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-503   VAL-504  4.3 4.6 -31.1 15.4 50.8 46.7 51.7
 VAL-504   LEU-505  5.2 5.5 11.5 -11.2 100.5 102.1 -8.7
 LEU-505   ARG-506  3.5 3.7 -5.2 19.0 47.4 54.2 -25.0
 ARG-506   LYS-507  0.4 0.1 -16.7 2.5 22.4 18.7 16.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees