Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
6.9
6.5
-7.5
-1.1
38.7
48.6
42.2
LYS-114
GLY-115
7.4
6.8
-17.2
0.6
77.2
73.4
19.4
GLY-115
PRO-116
4.1
3.8
14.5
-1.6
99.4
114.4
10.9
PRO-116
GLU-117
5.1
5.5
-81.5
83.5
16.3
26.9
-14.4
GLU-117
ILE-118
7.3
7.0
-3.6
-18.6
85.5
80.7
84.1
ILE-118
ARG-119
10.5
10.2
11.4
-12.8
119.4
124.0
0.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-215
ASP-216
10.5
10.6
-27.0
35.3
14.5
16.6
-41.9
ASP-216
LEU-217
11.3
11.8
-25.8
5.9
52.9
54.7
57.4
LEU-217
PRO-218
9.1
9.4
-20.5
-11.1
44.2
61.9
63.5
PRO-218
ALA-219
7.2
7.1
0.7
-13.5
70.8
72.1
-3.9
ALA-219
VAL-220
4.1
3.6
8.0
-1.0
90.2
127.9
-17.7
VAL-220
SER-221
2.7
3.0
-46.0
0.5
84.7
67.5
37.6
SER-221
GLU-222
6.2
6.4
0.0
17.1
150.4
147.9
-33.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees