DNA Polymerase Epsilon Catalytic Subunit A

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-979   GLU-980  26.9 25.8 17.5 -3.4 44.5 39.3 33.3
 GLU-980   LEU-981  26.0 24.7 1.6 1.6 59.0 67.9 24.9
 LEU-981   LYS-982  22.8 21.5 7.2 2.7 40.9 41.7 67.7
 LYS-982   GLY-983  23.3 22.2 0.8 -10.8 51.9 50.8 -67.9
 GLY-983   PHE-984  20.5 20.3 18.5 26.2 118.0 94.6 -202.2
 PHE-984   GLU-985  17.7 16.7 32.2 19.2 131.3 104.5 -206.7
 GLU-985   LEU-986  17.6 14.6 28.6 -123.2 161.8 161.9 677.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-991   LEU-992  13.2 13.9 -143.7 108.3 112.3 121.4 -97.5
 LEU-992   GLN-993  10.5 10.5 -23.8 13.3 155.9 154.7 -11.8
 GLN-993   LEU-994  10.2 10.2 -0.4 9.8 97.6 103.1 50.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-1035   MET-1036  10.9 10.2 -6.5 7.9 15.8 25.0 -16.4
 MET-1036   LEU-1037  9.0 7.8 67.3 -77.9 103.3 107.0 22.7
 LEU-1037   GLU-1038  7.3 7.3 -23.3 17.2 84.8 77.1 18.1
 GLU-1038   ASP-1039  10.2 9.8 -41.8 26.9 145.5 139.4 -91.1
 ASP-1039   GLU-1040  12.5 12.5 -3.8 3.9 93.2 98.1 32.3
 GLU-1040   ASP-1041  12.6 13.0 -12.2 20.1 105.6 109.7 33.0
 ASP-1041   LEU-1042  8.9 9.4 -1.3 1.1 162.3 163.1 10.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-1145   TYR-1146  5.3 4.7 -6.6 0.2 133.1 136.9 8.6
 TYR-1146   ARG-1147  4.1 3.6 -1.1 -1.0 91.4 96.0 7.7
 ARG-1147   GLU-1148  2.0 1.5 2.3 8.7 138.8 134.5 -6.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees