Proto-Oncogene Tyrosine-Protein Kinase Fes/fps

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-458   LEU-459  11.8 12.0 -4.2 -2.0 60.5 62.2 27.2
 LEU-459   TRP-460  10.4 10.3 3.6 0.9 59.6 59.5 51.7
 TRP-460   TYR-461  11.0 10.9 6.3 -13.0 29.5 29.4 -58.8
 TYR-461   HIS-462  8.6 8.6 -1.0 1.8 75.5 75.6 -3.9
 HIS-462   GLY-463  5.5 5.4 9.4 -12.5 46.3 43.2 -10.1
 GLY-463   ALA-464  3.5 3.5 6.8 1.1 62.4 69.5 75.8
 ALA-464   ILE-465  2.0 1.8 -4.6 20.3 60.7 62.4 93.7
 ILE-465   PRO-466  5.1 5.0 -21.7 -6.6 131.3 130.9 -253.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-470   ALA-471  11.5 11.5 3.2 8.6 109.9 105.5 -88.9
 ALA-471   GLU-472  15.1 15.0 -23.9 8.5 6.8 5.0 207.7
 GLU-472   LEU-473  14.3 14.4 4.5 -2.3 117.1 115.2 -44.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-483   GLU-484  7.2 7.1 -8.2 11.4 20.6 21.2 -19.1
 GLU-484   SER-485  5.0 5.0 18.3 14.6 113.6 114.0 -391.8
 GLN-489   GLU-490  3.3 5.0 85.8 -4.9 91.0 109.8 -281.8
 GLU-490   TYR-491  7.0 7.0 -42.2 4.4 165.2 157.9 -512.7
 TYR-491   VAL-492  8.8 8.6 2.6 -1.4 92.2 93.0 5.6
 VAL-492   LEU-493  10.6 10.5 -0.5 -0.4 150.2 147.9 -20.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-551   ASP-552  6.4 6.4 1.3 7.3 11.5 14.8 170.8
 ASP-552   LYS-553  5.1 5.2 1.6 -4.7 76.8 70.9 24.1
 LYS-553   TRP-554  2.5 2.8 0.9 -5.1 109.9 107.1 31.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-627   GLN-628  2.0 2.0 4.3 -4.9 59.4 58.3 16.9
 GLN-628   LYS-629  2.0 2.0 8.8 -10.1 17.8 21.3 14.1
 LYS-629   GLN-630  3.0 3.2 1.7 -8.1 83.1 82.2 43.6
 GLN-630   PRO-631  4.6 4.9 -5.1 -5.8 91.7 87.5 31.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees