Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  12.3 11.6 6.9 -0.4 73.9 73.1 0.6
 ILE-639   ALA-640  8.7 8.1 11.3 10.0 143.7 142.1 -21.5
 ALA-640   ASP-641  6.5 6.2 -30.7 8.2 104.0 102.4 5.0
 ASP-641   PHE-642  3.9 3.1 -36.3 -3.1 104.2 114.3 -19.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-661   LEU-662  12.4 14.2 21.4 51.6 112.2 76.4 -17.8
 LEU-662   PRO-663  9.5 12.1 -23.7 19.2 54.4 96.1 6.7
 PRO-663   VAL-664  7.6 8.7 -91.6 -6.7 18.0 48.6 117.8
 VAL-664   LYS-665  8.1 8.3 19.3 -8.2 131.2 133.3 -6.0
 LYS-665   TRP-666  7.3 7.2 4.9 2.6 83.6 79.6 -4.1
 TRP-666   MET-667  3.9 4.1 5.9 -3.0 93.1 88.8 3.7
 MET-667   ALA-668  3.8 3.5 -5.9 19.9 26.5 34.4 -14.0
 ALA-668   PRO-669  4.1 3.6 -1.6 -17.9 73.6 68.3 13.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees