Ionotropic Glutamate Receptor 5

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLY-109   ILE-110  2.4 2.8 23.0 -11.1 35.1 34.4 134.9  ILE-110   SER-111  3.2 3.4 6.4 -6.6 81.7 82.1 -33.1  SER-111   ILE-112  5.0 5.0 -5.9 5.5 144.3 143.0 -18.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-188   MET-189  6.3 6.6 4.6 -10.8 53.9 55.5 -121.6  MET-189   GLU-190  7.9 8.1 19.1 -5.3 22.9 17.7 219.9  GLU-190   SER-191  7.2 8.0 -19.5 5.3 113.6 110.6 -43.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-204   THR-205  17.9 17.9 3.3 0.4 136.6 133.3 -7.8  THR-205   GLN-206  15.5 15.5 1.0 -4.8 83.0 85.0 4.5  GLN-206   ILE-207  11.9 11.8 -9.5 17.2 114.3 114.2 71.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ILE-211   ASP-212  2.0 1.9 1.0 -0.2 68.1 67.0 46.2  ASP-212   SER-213  2.7 2.6 -1.7 9.0 161.9 162.2 74.8  SER-213   LYS-214  3.0 2.9 1.4 -0.9 68.6 70.2 -5.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees