Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-109   GLY-110  0.6 0.3 23.2 -3.9 58.6 63.3 75.2  LEU-109   GLY-110  4.5 4.6 23.2 -3.9 83.0 87.7 63.2  GLY-110   ILE-111  1.9 2.1 -7.3 5.5 20.2 18.6 11.9  LEU-109   GLY-110  0.6 0.3 23.2 -3.9 58.6 63.3 75.2  LEU-109   GLY-110  4.5 4.6 23.2 -3.9 83.0 87.7 63.2  GLY-110   ILE-111  1.9 2.1 -7.3 5.5 20.2 18.6 11.9  ILE-111   SER-112  3.2 3.4 13.4 -9.0 116.3 118.1 47.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-114   ILE-115  0.4 0.4 8.2 -2.2 32.7 32.7 82.8  ILE-115   LYS-116  2.4 2.2 9.4 -9.2 46.1 44.2 -10.1  LYS-116   LYS-117  2.0 2.0 -1.2 6.8 93.8 91.0 45.3  LYS-117   GLY-118  5.8 5.7 4.7 -19.4 137.0 127.2 126.5  LYS-117   GLY-118  5.8 5.7 4.7 -19.4 137.0 127.2 126.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-117   GLY-118  5.8 5.7 4.7 -19.4 137.0 127.2 126.5  LYS-117   GLY-118  5.8 5.7 4.7 -19.4 137.0 127.2 126.5  GLY-118   THR-119  7.8 8.1 11.3 -2.1 70.8 75.6 -19.1  THR-119   PRO-120  7.5 7.4 1.5 1.4 51.5 52.2 77.7 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ARG-180   VAL-181  7.5 7.6 -1.3 1.1 91.8 88.3 -14.4  VAL-181   ARG-182  3.9 4.0 -2.4 3.3 144.2 142.0 3.9  ARG-182   LYS-183  3.6 3.5 -7.1 18.9 156.6 155.3 140.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LYS-185   GLY-186  3.5 3.3 7.0 -6.3 57.5 50.1 -0.7  GLY-186   LYS-187  4.9 4.8 -6.0 11.8 111.6 104.4 42.4  LYS-187   TYR-188  7.7 7.6 -2.4 -3.6 142.3 137.8 -34.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  TYR-190   LEU-191  5.3 5.2 -2.0 -0.4 18.2 12.9 29.5  LEU-191   LEU-192  5.5 5.8 -3.6 -4.8 70.5 68.8 56.3  LEU-192   GLU-193  5.2 5.5 -14.6 6.7 39.6 44.4 90.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-215   ASP-216  9.5 9.6 -3.3 -0.1 37.9 31.8 13.8  ASP-216   SER-217  6.7 6.8 -1.6 3.1 98.7 97.6 12.1  SER-217   LYS-218  2.9 3.0 0.0 -25.0 81.9 76.4 76.3  LYS-218   GLY-219  3.6 3.1 12.6 -0.4 72.1 56.2 40.0  GLY-219   TYR-220  4.9 5.0 16.9 -7.1 64.5 69.3 0.9  LEU-215   ASP-216  5.0 5.0 -3.3 -0.1 154.6 163.6 -27.2  ASP-216   SER-217  3.8 3.7 -1.6 3.1 105.5 106.3 -4.3  SER-217   LYS-218  1.7 1.2 0.0 -25.0 108.8 114.2 -305.5  LYS-218   GLY-219  5.2 4.5 12.6 -0.4 84.3 99.2 37.1  LEU-215   ASP-216  9.5 9.6 -3.3 -0.1 37.9 31.8 13.8  ASP-216   SER-217  6.7 6.8 -1.6 3.1 98.7 97.6 12.1  SER-217   LYS-218  2.9 3.0 0.0 -25.0 81.9 76.4 76.3  LYS-218   GLY-219  3.6 3.1 12.6 -0.4 72.1 56.2 40.0  GLY-219   TYR-220  4.9 5.0 16.9 -7.1 64.5 69.3 0.9  GLY-213   ASN-214  6.3 6.2 7.3 -8.1 82.3 83.1 -28.2  ASN-214   LEU-215  3.0 2.9 4.7 7.9 66.6 68.1 55.3  LEU-215   ASP-216  5.0 5.0 -3.3 -0.1 154.6 163.6 -27.2  ASP-216   SER-217  3.8 3.7 -1.6 3.1 105.5 106.3 -4.3  SER-217   LYS-218  1.7 1.2 0.0 -25.0 108.8 114.2 -305.5  LYS-218   GLY-219  5.2 4.5 12.6 -0.4 84.3 99.2 37.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees