Proto-Oncogene Tyrosine-Protein Kinase Src

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-254   LEU-255  13.0 12.1 -12.6 19.4 80.8 98.9 0.2
 LEU-255   ALA-256  11.0 11.0 177.1 -93.1 159.9 152.1 -63.1
 ALA-256   LYS-257  10.6 10.2 20.5 77.4 80.4 128.8 -6.5
 LYS-257   ASP-258  7.0 9.2 -35.6 -170.6 39.4 100.1 51.2
 ASP-258   ALA-259  6.5 6.5 -158.8 -23.3 84.2 140.7 50.1
 ALA-259   TRP-260  5.3 5.6 125.8 -64.3 38.8 51.9 50.9
 TRP-260   GLU-261  5.8 5.5 -60.3 -21.3 114.0 130.5 -12.8
 GLU-261   ILE-262  2.1 2.9 -39.1 32.9 77.2 84.2 9.2

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees