Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
6.4
6.1
1.9
-13.7
135.6
128.9
47.0
LYS-114
GLY-115
6.1
5.4
-10.9
-14.6
74.3
71.3
29.9
GLY-115
PRO-116
2.4
1.9
16.4
9.6
95.3
114.8
-31.4
PRO-116
GLU-117
3.5
4.0
-102.8
99.2
22.9
37.3
11.1
GLU-117
ILE-118
6.0
5.5
-3.2
-24.4
90.2
86.4
56.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-215
ASP-216
10.5
10.5
-24.6
26.9
21.2
25.9
-42.1
ASP-216
LEU-217
11.3
11.7
-34.5
11.1
48.2
44.3
77.9
LEU-217
PRO-218
8.6
8.8
-12.5
-22.3
49.8
77.0
78.5
PRO-218
ALA-219
6.9
6.8
-5.4
-6.5
112.4
103.1
-19.1
ALA-219
VAL-220
5.0
3.9
24.7
-16.2
93.7
131.5
-47.7
VAL-220
SER-221
1.6
2.1
-56.4
18.9
78.3
59.1
40.0
SER-221
GLU-222
3.9
4.2
1.8
8.9
154.1
154.3
-11.1
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees