Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 MET-537   ILE-538  3.2 3.6 -12.6 8.9 80.6 78.1 -18.4
 ILE-538   GLY-539  0.4 1.0 -1.6 4.3 74.9 74.2 1.1
 GLY-539   LYS-540  3.8 4.4 9.3 -22.1 150.1 155.3 51.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-542   ASN-543  9.1 8.8 4.4 4.6 61.1 64.3 16.0
 ASN-543   ILE-544  7.9 7.9 7.5 -10.5 102.7 104.8 7.1
 ILE-544   ILE-545  4.4 4.4 20.6 -9.2 56.0 60.5 13.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLU-562   TYR-563  3.9 3.8 8.2 -26.6 138.3 137.6 69.9
 TYR-563   ALA-564  2.6 2.5 5.1 -8.1 104.0 114.7 16.1
 ALA-564   SER-565  1.4 1.5 7.0 -7.7 163.8 158.0 -32.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-636   MET-637  10.0 9.7 -5.4 -0.6 72.1 72.9 17.2
 MET-637   LYS-638  9.2 9.1 -7.0 1.3 46.9 40.1 28.7
 LYS-638   ILE-639  5.9 6.0 11.4 -3.2 109.9 107.0 -18.4
 ILE-639   ALA-640  6.5 6.5 -0.1 19.5 87.0 87.8 -6.1
 ALA-640   ASP-641  5.5 5.5 -28.1 -0.9 68.9 51.7 68.9
 ASP-641   PHE-642  8.1 7.3 16.7 -54.6 166.8 149.9 246.0
 PHE-642   GLY-643  7.9 6.6 -9.2 -42.4 67.3 49.5 90.6
 GLY-643   LEU-644  11.2 6.7 7.0 34.8 131.3 96.6 -119.2
 LEU-644   ALA-645  12.9 10.4 133.5 -52.1 139.2 143.8 -441.2
 GLY-660   ARG-661  24.1 18.5 -102.1 -75.6 128.0 105.5 840.0
 ARG-661   LEU-662  22.5 21.4 -51.2 -140.3 71.5 54.3 -573.9
 LEU-662   PRO-663  21.3 23.3 -59.6 1.8 132.8 58.1 -96.6
 PRO-663   VAL-664  20.3 20.8 -82.4 -15.3 70.0 47.3 292.4
 VAL-664   LYS-665  23.5 23.7 11.5 -1.5 72.6 82.3 -27.0
 LYS-665   TRP-666  23.8 24.3 1.6 6.3 110.8 111.6 -15.0
 TRP-666   MET-667  20.8 21.1 -9.0 12.3 1.1 0.9 -26.7
 MET-667   ALA-668  21.6 21.7 2.6 3.6 118.8 117.7 30.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees