Metabotropic Glutamate Receptor 8

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PRO-197   PRO-198  3.6 3.8 -8.2 -0.9 24.0 23.2 55.8
 PRO-198   ASP-199  3.5 3.9 -0.9 -1.4 92.3 91.6 2.0
 ASP-199   SER-200  3.1 3.5 2.5 -8.1 90.1 93.6 -1.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PRO-333   LYS-334  2.5 2.2 -5.5 -6.0 22.0 25.4 76.7
 LYS-334   ARG-335  2.2 2.0 7.4 -3.0 95.5 94.8 -105.8
 ARG-335   ALA-336  5.7 5.5 -14.8 -4.2 35.2 31.7 121.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-464   GLY-465  13.4 14.0 -5.6 12.0 103.1 97.1 -5.6
 GLY-465   ASP-466  12.6 12.8 -7.3 7.0 106.6 109.4 -3.1
 ASP-466   ALA-467  9.3 9.5 -9.0 12.1 173.2 176.2 9.6
 ALA-467   PRO-468  7.6 8.0 -2.3 0.0 95.4 102.3 -11.6
 PRO-468   GLY-469  7.1 7.6 -3.4 4.0 85.1 87.5 11.2
 GLY-469   ARG-470  5.1 5.5 -1.7 11.9 148.7 155.0 41.5
 ARG-470   TYR-471  3.2 3.4 -3.8 2.3 83.0 78.9 8.0
 TYR-471   ASP-472  3.5 3.3 -0.6 3.8 138.9 138.6 5.6
 ASP-472   ILE-473  6.0 5.7 -4.4 -5.4 55.2 57.4 44.8
 ILE-473   PHE-474  9.7 9.4 -11.4 5.9 117.2 115.1 -39.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees